Authors

Hypoglycemic effects of Pleurotus ostreatus polysaccharides

DOI: 10.17586/1606-4313-2019-18-2-72-78
UDC 561.284; 615.272

Hypoglycemic effects of Pleurotus ostreatus polysaccharides

Antontceva Е.V., Sorokin S.S., Shamtsyan M.M., Chefu Svetlana G., Petrischev Nikolay N., Konusova Valentina G.

For citation: Antontceva Е.V., Sorokin S.S., Shamtsyan М.M., Chefu S.G., Petrischev N.N., Konusova V.G. Hypoglycemic effects of Pleurotus ostreatus polysaccharides. Vestnik Mezhdunarodnoi akademii kholoda. 2019. No 2. p.72-78

Abstract
The effect of the preparation obtained from submerged biomass of Pleurotus ostreatus fungus on hyperglycemia in animals is studied. Preparation containing water-soluble β-glucans has been obtained by the method of sequential ethanolic and aqueous extraction. The content of β-glucans in the obtained preparation has been determined. A study of possible hypoglycemic action on healthy animals shows that taking the preparation does not affect the serum glucose level. Te blood serum glucose level of diabetic animals receiving β-glucan containing preparation is significantly lower than for diabetic animals without receiving the preparation. A reduction of serum glucose level in diabetic animals is shown. A possible mechanism for this action is described. The preparation containing β-glucans of the fungus P. ostreatus can be used as the basis for the development of biologically active supplement and functional foods with hypoglycemic action.

Keywords: Pleurotus ostreatus, β-glucans, submerged cultivation, diabetes, hypoglycemic action, streptozotocin induced diabetes.

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