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Reserving components of the blood and hematopoietic cells using low temperatures: current status and prospects for implementation in the interests of victims in emergency situations

UDC 62–9

Reserving components of the blood and hematopoietic cells using low temperatures: current status and prospects for implementation in the interests of victims in emergency situations

Bagautdinov Sh. M. , Popova N. N., Vilyaninov V. N., Kaleko S. P., Semelev V. N., Sidorkevich S. V., Petrenko G. I.

Abstract
The basic stages of evolution of understanding of the basic mechanisms of human blood cell cryopreservation are discussed. Analysis of modern cryopreservation technologies and applied cryoprotective solutions is presented. Researches in the filed of cryopreservation made with the help of specialists from Army medical college of MAUD RF are listed. Perspective directions of researches in the field of blood and bone marrow cell cryopreservation and optimal solutions are shown. There exist the possibility of creating and implementing high effective methods of producing allogeneic and autogenic blood parts and their reserving by freezing at –150…–196 oС, –65…–80 oС and –25…–40 oС. Modern trends for cryopreservation and cryophilactic research aiming to provide maximum morphofunctional preservation and clinical effectiveness of red blood cells application are shown.

Keywords: cryopreservation, human red blood cells, glycerol, platelets.

All references

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