Authors

Extraction of crude Mannan oligosaccharides from yeast and their uses

DOI: 10.17586/1606-4313-2020-19-1-46-51
UDC 577.114; 663.45

Extraction of crude Mannan oligosaccharides from yeast and their uses

Harbah Razan, Agembo Evans Odongo , Meledina T.V., Kritchenkov A.S., Ivanova Vera A.

For citation: Harbah R., Agembo E.O., Meledina T.V., Kritchenkov A.S., Ivanova V.A. Extraction of crude Mannan oligosaccharides from yeast and their uses. Vestnik Mezhdunarodnoi akademii kholoda. 2020. No 1. p.46-51

Abstract
This review aims to emphasize the importance of mannan oligosaccharides, obtained from various resources especially from yeasts. Attractive features of mannan polysaccharides have had influenced the decisions of food scientists to pursue research on this element, and that may expand their uses and applications in medicine, food industry and animals feed. Food researchers are increasingly focusing on yeast cell wall (YCW) as a promising source of mannan extraction, as the yeast extracts sector generates a huge amount of YCW as a by-product. Extraction is an important method used to obtain the water-soluble mannan oligosaccharides from the wall cells of yeast and in this review was showed the optimal conditions for the extraction of mannan from cell yeast according to results some of the scientific studies along with the deproteinization methods. In the fооd industry, mаnnаn has various аррliсаtiоns such as viscosity modifiers, stabilizers, and increasing the thermo-stability of anthocyanins. Mannan has many health benefits, which have expanded its uses in the medical and pharmaceutical fields. In the animal feed sector, several studies of farm animals have shown significant positive effects of weight gain, reduced bird mortality, and improved fish growth. In pigs, the addition of mannan to pig diets led to obvious economic benefits.

Keywords: mannan, oligosaccharides, yeast cell wall, extraction, prebiotic, food industry, feed additives.

All references

1. Korolenko, T.A., Bgatova, N.P. & Vetvicka, V. (2019). Glucan and Mannan– Two Peas in a Pod.International journal of molecular sciences,20(13), 3189.

2. Patel, S.& Goyal, A. (2011). Functional oligosaccharides: production, properties and applications.World Journal of Microbiology and Biotechnology,27(5), 1119-1128.

3. Mora-Montes, H.M., Bates, S., Netea, M.G., Castillo, L., Brand, A., Buurman, E.T. & Gow, N. A. (2010). A multifunctional mannosyltransferase family in Candida albicans determines cell wall mannan structure and host-fungus interactions. Journal of Biological Chemistry, 285(16), 12087-12095.

4. Rodrı´guez-Gacio, M.C., Iglesias-Fernandez, R., Carbonero, P., & Matilla, A.J. (2012). Softening-up mannan-rich cell walls. J Exp Bot, 63, 3976-3988.

5. Bzducha-Wro´bel, A., Kieliszek, M., & Błazejak, S. (2013). Chemical composition of the cell wall of probiotic and brewer’s yeast in response to cultivation medium with glycerol as a carbon source. Eur Food Res Technol, 237, 489–499. DOI 10.1007/s00217-013-2016-8.

6. Scheller, H.V. & Ulvskov, P. (2010). Hemicelluloses. Annu Rev Plant Biol, 61, 263-89.

7. Šandula, J.; Kogan, G.; Kacˇuráková, M.; Machová, E. Microbial (1→3)-β-d-glucans, their preparation, physico-chemical characterization and immunomodulatory activity. Carbohydr. Polym. 1999, 38, 247-253.

8. Machova, E.; Fiacanova, L.; Cizova, A.; Korcova, J. Mannoproteins from yeast and hyphal form of Candida albicans considerably diﬀer in mannan and protein content. Carbohydr. Res. 2015, 408, 12-17.

9. Varona R., Perez P. & Duran A. (1983) Effect of papulacandin B on β-glucan synthesis in Schizosaccharomyces pombe. FEMS Microbiol. Lett. 20: 243-247.

10. Spring, P., Wenk, C., Connolly, A. & Kiers, A. A review of 733 published trials on Bio-Mos®, a mannan oligosaccharide, and Actigen®, a second generation mannose rich fraction, on farm and companion animals. Journal of Applied Animal Nutrition, 2015. vol. 3. P. 1-11.

11. Ganner, A. & Schatzmayr, G. (2012). Capability of yeast derivatives to adhere enteropathogenic bacteria and to modulate cells of the innate immune system. Appl. Microb. Biotechnol., 95, 289-297.

12. Torrecillas, S., Makol, A., Caballero, M. J., Montero, D., Robaina, L., Real, F. & Izquierdo, M. S. (2007). Immune stimulation and improved infection resistance in European sea bass (Dicentrarchus labrax) fed mannan oligosaccharides. Fish & Shellfish Immunology, 23(5), 969-981.

13. Staykov, Y., Spring, P., Denev, S. & Sweetman, J. (2007). Effect of a mannan oligosaccharide on the growth performance and immune status of rainbow trout (Oncorhynchus mykiss).Aquaculture International, 15(2), 153-161.

14. Burr, G., Hume, M., Neill, W.H., & Gatlin III, D.M. (2008). Effects of prebiotics on nutrient digestibility of a soybean‐meal‐based diet by red drum Sciaenops ocellatus (Linnaeus).Aquaculture Research,39(15), 1680-1686.

15. Li, J. & Karboune, S. (2018). A comparative study for the isolation and characterization of mannoproteins from Saccharomyces cerevisiae yeast cell wall. International journal of biological macromolecules, 119, 654-661.

16. Chae, H.J., Joo, H., & In, M.J. (2001). Utilization of brewer's yeast cells for the production of food-grade yeast extract. Part 1: effects of different enzymatic treatments on solid and protein recovery and flavor characteristics. Bioresource technology, 76(3), 253-258.

17. Borchani, C., Fonteyn, F., Jamin, G., Paquot, M., Blecker, C., & Thonart, P. (2014). Enzymatic process for the fractionation of baker’s yeast cell wall (Saccharomyces cerevisiae). Food chemistry, 163, 108-113.

18. Huang, G., Yang, Q. & Wang, Z.B. (2010). Extraction and deproteinization of mannan oligosaccharides. Zeitschrift für Naturforschung C, 65(5-6), 387-390.

19. Quirós, M., Morales, P., Pérez-Través, L., Barcenilla, J.M. & Gonzalez, R. (2011). A new methodology to determine cell wall mannoprotein content and release in wine yeasts. Food chemistry, 125(2), 760-766.

20. Huang, G.L., Liu, M.X. & Mei, X.Y. (2005). Studies on the hydrolytic condition of β-1,3 glucan from yeast by fluorophore-assisted carbohydrate electrophoresis. Anal. Lett. 38, 477-485.

21. Liu, H., Li, Y., Shi, A., Hu, H., Sheng, X., Liu, L. & Adhikari, B. (2018). Rheological characteristics and chain conformation of mannans obtained from Saccharomyces cerevisiae. International journal of biological macromolecules, 107, 2404-2411.

22. Lipke, P.N. & Ovalle, R. (1998). Cell wall architecture in yeast: new structure and new challenges. Journal of bacteriology, 180(15), 3735-3740.

23. Fowler, J., Kakani, R., Haq, A., Byrd, J.A., & Baily, C.A. (2015). Growth promoting effects of prebiotic yeast cell wall products in starter broilers under an immune stress and Clostridium perfringens challenge. J. Appl. Poult. Res. 24, 66-72.

24. Kwiatkowski, S. & E. Kwiatkowski, E. (2012). Yeast (Saccharomyces cerevisiae) glucan polysaccharides – occurrrence, separation and application in food, feed and health industries. In Karunaratne, D.N. (ed) The complex world of polysaccharides. InTech, pp. 47-70.

25. Van der Werf, M.J. (2019). MOS products: Not every yeast cell wall is created equal. Ohly Application. Retrieved from www.ohly.com/en/feed-health.

26. Éder Galinari, Diego Araújo Sabry, Guilherme Lanzi Sassaki, Gorete Ribeiro Macedo, Flávia Maria Lopes Passos, Hilário Cuquetto Mantovani, Hugo Alexandre Oliveira Rocha. Chemical structure, antiproliferative and antioxidant activities of a cell wall α-D-mannan from yeast Kluyveromyces marxianus. Carbohydrate Polymers.2016. Vol. 157, 1298-1305.

27. Yamabhai, M., Sak-Ubol, S., Srila, W. & Haltrich, D. (2013). Mannan biotechnology: from biofuels to health. Critical Review in Biotechnology, 1-11.

28. Onitake,T.;Ueno,Y.;Tanaka,S.;Sagami,S.;Hayashi,R.;Nagai,K.;Hide,M.;Chayama,K. Pulverized konjac glucomannan ameliorates oxazolone-induced colitis in mice. Eur. J. Nutr. 2015, 54, 959–969.

29. Korolenko T.A., Johnston T.P., Machova E., Bgatova N.P., Lykov A.P., Goncharova N.V., Nescakova Z., Shintyapina A.B., Maiborodin I.V., Karmatskikh O.L. Hypolipidemic effect of mannans from C. albicans serotypes a and B in acute hyperlipidemia in mice.International Journal of Biological Macromolecules.2018,107, 2385-2394.

30. Roberfroid M, Gibson GR, Hoyles L, et al. (2010). Prebiotic effects: metabolic and health benefits. Br J Nutr, 104, s1-s63.

31. Ghosh, S.; Mehla, R.K. Inﬂuence of dietary supplementation of prebiotics (mannanoligosaccharide) on the performance of crossbred calves. Trop. Anim. Health Prod. 2012, 44, 617–622.

32. Loginova,V.M.;Tuzikov,F.V.;Tuzikova,N.A.;Korolenko,T.A.Comparativecharacteristicsoflipemiamodels induced by injections of Triton WR-1339 and poloxamer 407 in mice. Bull. Exp. Biol. Med. 2013, 155(2), 284-287.

33. Hoving, L.R.; Katiraei, S.; Heijink, M.; Pronk, A.; van der Wee-Pals, L.; Streeﬂand, T.; Giera, M.; Willems van Dijk, K.; van Harmelen, V. Dietary mannan oligosaccharides modulate gut microbiota, increase fecal bile acid excretion, and decrease plasma cholesterol and atherosclerosis development. Mol. Nutr. Food. Res. 2018, 62, e1700942.

34. Pukrop, J.R.; Brennan, K.M.; Funnell, B.J.; Schoonmaker, J.P. Eﬀect of a hydrolyzed mannan and glucan rich yeast fraction on performance and health status of newly received feedlot cattle. J. Anim. Sci. 2018, 96, 3955-3966.

35. Credence Research, Inc. (2018). Global prebiotics market – growth, future prospects, and competitive Analysis, 2018-2026. Retrieved from https://www.credenceresearch.com/report/prebiotics-market.

36. Piotrowska, M. & Masek, A. (2015). Saccharomyces cerevisiae cell wall components as tools for ochratoxin A decontamination. Toxins. 7, 1151-1162.

37. Campbell, J.M., Crenshaw, J.D., & Polo, J. (2013). The biological stress of early weaned piglets. J. Anim. Sci. Biotechnol. 4, 19.

38. Taylor-Pickard. (2015). The influence of MOS on sow and piglet performance. Int. Anim. Health J., 2, 60-63.

39. Berge, A.C. (2016). A meta-analysis of the inclusion of Bio-Mos® in milk or milk replacer fed to dairy calves on daily weight gain in the pre-weaning period. J. Animal Res. Nutrition, 1, 19.

40. Hooge, D.M., Kiers, A. & Connolly, A. (2013). Meta-analysis summary of broiler chicken trials with dietary Actigen® (2009-2011). Int. J. Poultry Sci. 12, 1-8.

41. Al-Manhel, A.J. & Niamah, A.K. (2017). Mannan extract from Saccharomyces cerevisiae used as prebiotic in bioyogurt production from buffalo milk. International Food Research Journal, 24(5).

42. Jane Wu, YongguangGuan, Xin Zhong.(2015). Yeast mannoproteins improve thermal stability of anthocyanins at pH7.0,Food chemistry.172,121-128.

43. Cerqueira, M.A., Souza, B.W.S., Simoes, J., Teixeira, J.A., Domingues, M.R.M., Coimbra, M.A., Vicente, A.A. (2011). Structural and thermal characterization of galactomannans from non-conventional sources. Carbohydrate Polymers. 83, 179-185.

Read the full article